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Levetiracetam: Uses, Side Effects and Precautions

Levetiracetam is a prescription medicine that helps prevent seizures caused by epilepsy.

What should I know about Levetiracetam?

Keep taking it for as long as your doctor advises. If you are told to stop, the dose is usually reduced gradually.

What are the side effects?

Dizziness, sleepiness, headaches, nausea, shaking, and feeling agitated or irritable can occur. Avoid driving if you feel sleepy or dizzy.

Who should check first?

Tell your doctor if you have kidney problems, have had depression or thoughts of self-harm, or are pregnant, planning pregnancy or breastfeeding. Macrogol, methotrexate and St John’s wort may not mix well with it.

When should I get help?

Seek urgent help for blistering or peeling skin, very little urine, or swollen legs. If you have thoughts of harming yourself, seek urgent professional help. If you may act on them or have seriously harmed yourself, call your local emergency services immediately. Call your local emergency number (000 in Australia) for swelling of the throat or tongue, or trouble breathing.

Doses vary, so follow your prescriber, pharmacist and the medicine label. In Australia, call 000 in an emergency. Outside Australia, use your local emergency number.

Source: NHS: About levetiracetam. General education does not replace individual medical advice. Updated November 2026.

Explore our health guides and medicine FAQs. Medicine availability and product instructions vary by country; follow the leaflet supplied with your medicine.

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