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Doxycycline is an antibiotic used for bacterial infections, and sometimes for acne, rosacea or malaria prevention. Take it only if it has been prescribed for you, and finish the course as directed.
How is it taken?
For standard tablets or capsules, swallow whole with a glass of water while sitting or standing. Dispersible tablets must be dissolved in water as the leaflet directs. Stay upright for at least 30 minutes after taking a dose. Check your own leaflet for food instructions.
What are the side effects?
Headache, nausea, vomiting and rash can occur. Increased sun sensitivity can also occur, so report any rash, itching or redness.
Who should check first?
Tell your doctor if you have liver or kidney problems, lupus, myasthenia gravis or alcohol dependence, or are pregnant or breastfeeding. It is not usually given to children under 12, as it can affect tooth development.
Can it interact with other medicines?
Yes, including warfarin, antacids, acne medicines, and products containing iron or zinc. Avoid alcohol.
When should I get help?
Seek urgent advice for stomach pain with bloody diarrhoea, easy bruising, or frequent illness. Call your local emergency number (000 in Australia) for sudden swelling of the lips, mouth, throat or tongue, trouble breathing, or fainting.
Doses vary, so follow your prescriber, pharmacist and the medicine label. In Australia, call 000 in an emergency, or the Poisons Information Centre on 13 11 26 for a possible overdose. Outside Australia, use your local emergency and poison-information services.
Source: NHS: Doxycycline. General education does not replace individual medical advice. Updated November 2026.
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