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Clotrimazole: Uses, Side Effects and Precautions

Clotrimazole is an antifungal medicine. It is used for fungal infections such as thrush, athlete’s foot, ringworm and intertrigo. It comes as creams, pessaries, solution and spray.

How is the external cream usually used?

External creams are usually applied in a thin layer 2 or 3 times a day for 2 to 4 weeks. Wash your hands before and after. Directions differ by product, so follow your pack.

What are the side effects?

On the skin, it can cause redness, itching, pain, burning or stinging. Vaginal products can cause burning, swelling, pelvic pain, discharge or bleeding.

Who should check before treating thrush?

Speak to a pharmacist or doctor if you are 15 or under, over 60, have had vaginal thrush more than twice in 6 months, have had an STI, or have abnormal discharge, sores, ulcers, blisters or bleeding. Check first if you are pregnant or breastfeeding.

Can it affect condoms?

Yes. Cream and pessaries can damage latex in condoms and diaphragms, and they may be less effective for at least 5 days after treatment ends.

When should I see a doctor?

See a doctor if symptoms have not improved after 7 days. Call triple zero (000) for sudden swelling of the lips, mouth, throat or tongue, trouble breathing, or fainting.

Doses vary, so follow your prescriber, pharmacist and the medicine label. In an emergency, call triple zero (000). For a possible overdose, call the Poisons Information Centre on 13 11 26.

Source: NHS: Clotrimazole. General education does not replace individual medical advice. Updated November 2026.

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