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Sitagliptin is a prescription tablet for type 2 diabetes in people whose blood sugar stays high despite a healthy diet and regular exercise.
What should I know about Sitagliptin?
It raises the amount of insulin the body makes, and starts working within a few hours.
What are the side effects?
Headache can occur. Serious side effects are uncommon but need prompt attention; see the warning signs below.
Who should check first?
Tell your doctor about your medical conditions and all your medicines, and if you are pregnant or breastfeeding.
When should I get help?
Seek emergency care for severe persistent stomach or back pain, a blistering rash or mouth sores, or breathing difficulty. These can indicate serious reactions such as pancreatitis or a severe skin reaction. Call your local emergency number (000 in Australia) for swelling of the throat or tongue, or trouble breathing.
Doses vary, so follow your prescriber, pharmacist and the medicine label. In Australia, call 000 in an emergency. Outside Australia, use your local emergency number.
Source: NHS: About sitagliptin. General education does not replace individual medical advice. Updated November 2026.
Explore our health guides and medicine FAQs. Medicine availability and product instructions vary by country; follow the leaflet supplied with your medicine.